Bask in big city lights of Los Angeles and Las Vegas, wind through the streets of San Francisco, hike through Yosemite, feel the heat in Death Valley, get your kicks on Route 66
From ghost towns and the Grand Canyon to roadside burger joints and the cosmopolitan streets of San Francisco, this region is loaded with the intriguing and the incredible. Best of all, this Los Angeles to San Francisco itinerary is structured so that those short on time can experience the region's best. At the sights—like the atmospheric mining town of Laughlin—you’ll get great pictures and a greater appreciation of what you’re seeing. Best of all, national park entrances are included, so you can explore Yosemite and still try your luck in Las Vegas.
Now you can book your flights and your trip at the same time in one simple online transaction. Click, click, click, go! Easy!
This trip also runs in reverse from San Francisco to Los Angeles. See Western Express Southbound
This tour runs year round with slight variations in summer and winter. If you are travelling mid-June through October, you will be on the summer itinerary. If you are travelling from Nov 1 to mid-June, you will be follow the winter itinerary. Additionally, we may revert to the winter itinerary in the shoulder seasons in the event of inclement weather.
Arrive at any time.
Keep your eyes peeled for celebs as you head out of town.
Take a short hike (weather permitting) along the rim of the Grand Canyon or opt for a helicopter tour. Sunset pizza dinner at the rim.
Travel to Sin City, stopping at a traditional roadside burger joint along the way. Enjoy exploring the Vegas strip, then opt for a limousine tour or try your luck at the slots.
Head to desolate Death Valley—the hottest, driest and lowest spot in North America.
In summer, travel via Tioga Pass and enjoy and the view of Mono Lake and the Tufa Towers. In winter or inclement weather, follow an alternate route through the Sierras. Arrive in Yosemite for trekking (weather permitting) amongst the giant sequoias.
Enjoy an orientation of San Francisco, including attractions like Fisherman's Wharf and the stately Golden Gate Bridge.
Depart at any time. We highly recommend booking pre- and post-accommodation to fully experience these famous cities.
Find dates, prices, and more trip options.Book Now